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Study looks at which foods prevent cancer vs. those that contribute to it

cancer foodsOne of the key challenges in preventing cancers and other chronic diseases is helping consumers make healthier food choices. For this reason, some countries are considering implementing a simplified labeling system that informs consumers of the nutritional quality of food products. The Nutri-Score is France’s official nutrition label, but it remains optional as per European labeling regulations. It is a five-color nutrition label that was based on the Nutrient Profiling System of the British Food Standards Agency modified version (FSAm-NPS) score.

To test the relevance of the two labels as nutritional profiling systems, a team of European researchers conducted a prospective analysis of the association between the nutritional score of food and cancer risk. Their study involved a large and diverse European population that constitutes the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The EPIC study is an ongoing multi-center prospective cohort study investigating metabolic, dietary, lifestyle, and environmental factors in relation to cancer and other chronic diseases.

The research team analyzed the association between the FSAm-NPS score – which reflects their nutritional quality – and cancer risk in 471,495 adults from 10 European countries; 49,794 of them were newly diagnosed cancer cases. They calculated the FSAm-NPS score for each food or beverage using its 100-gram content in energy, sugar, saturated fatty acid, sodium, fibers, proteins, and fruits/vegetables/legumes/nuts. The FSAm-NPS scores of all food items typically consumed by an individual were averaged to obtain the individual FSAm-NPS Dietary Index (DI) scores. A high FSAm-NPS DI score indicates low nutritional quality.

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The researchers found that consumption of foods with high FSAm-NPS DI scores was associated with high risks of developing cancers, such as colorectal, lung, liver, and breast cancer. This finding supports the relevance of using the FSAm-NPS and Nutri-Score to grade the nutritional quality of food products as a basis for prevention strategies for cancer and other diseases. The results of this study were published in the journal PLOS Medicine.

How your diet influences your risk of cancer

Increasing evidence suggests that the foods you eat can either increase or decrease your risk of cancer. Adhering to a diet rich in whole foods like fruits, vegetables, whole grains, legumes, spices, healthy fats, fresh fish, and high-quality dairy may reduce cancer risk. (Related: Nine anti-cancer foods proven to prevent and help reverse cancer.)

Conversely, high consumption of certain foods may raise your chances of developing cancer. Some of these cancer-causing foods contain high amounts of sugar and refined carbs. A review published in the Nutrition Journal reported that processed foods high in sugar but low in fiber and nutrients have been linked to increased cancer risk.

Eating lots of processed and red meats can also increase the risk of certain cancers including colon, stomach, and pancreatic cancers. Processed meat includes ham, bacon, salami, and sausages, while red meat includes all fresh, minced, and frozen beef, pork, and lamb.

Researchers found that processed and red meats can increase the risk of cancer because of their chemical content – that is, chemicals that are naturally present in the meat or were used to preserve the meat, and the chemicals produced when the meat is cooked at high temperatures. Red meat contains a naturally occurring red pigment called haem, which could irritate or impair cells or increase the production of harmful chemicals by bacteria, thus increasing the risk of cancer. On the other hand, nitrates and nitrites are chemicals often used to preserve processed meat. The body converts nitrites into cancer-causing chemicals called N-nitroso compounds (NOCs). Cooking meat at high temperatures, such as grilling or barbecuing, also produces chemicals called heterocyclic amines (HCAs) and polycyclic amines (PCAs) – both of which cause cancer.

Lower your risk of cancer and other diseases by eating healthily. Learn more at Prevention.news.

Sources include:

Science.news

Healthline.com

CancerResearchUK.org

Originally posted: https://www.naturalnews.com/2019-06-12-foods-that-prevent-cancer-and-foods-that-contribute-to-it.html

Compound from aged garlic demonstrates anti-cancer activity

black garlicResearchers from Fujian Normal UniversityShenzhen Third People’s Hospital, and The University of Hong Konglooked at the anti-cancer activity of a compound in aged garlic called S-allylmercaptocysteine (SAMC) in a review of studies. They published their findings in the Chinese Journal of Natural Medicines.

  • Daily consumption of food supplements with anti-cancer potential has become a way to prevent and manage cancer.
  • Emerging evidence supports a link between garlic consumption and decreased cancer incidence.
  • Notably, aged garlic extract (AGE) has stronger anti-cancer activities than that of fresh garlic, because it is enriched with AGE-specific organosulfur compounds, such as SAMC.
  • In this review, the researchers looked at studies on SAMC and its anti-cancer potential.
  • They summarized the up-to-date mechanistic pathways associated with the anti-proliferative, anti-metastatic and pro-apoptotic effects of SAMC in various cancer models.
  • Evidence suggested that SAMC can protect against cancer because of its ability to eliminate reactive oxygen species (ROS) and increase antioxidant enzymes.
  • SAMC also exhibits anti-tumor effects by activating mitogen-activated protein kinase (MAPK), scavenging active oxygen, and inhibiting inflammation.
  • SAMC can induce Bcl-2 family imbalance to cause programmed cell death of tumor cells.
  • It can also inhibit tumor cell proliferation and suppress tumor cell invasiveness.
  • Additionally, it can increase the chemosensitivity of cancer cells.

Based on the evidence gathered, the researchers concluded that SAMC in aged garlic can be used as a promising daily food supplement for preventing and treating cancer.

Read the full text of the study at this link.

For more studies on food supplements that have anti-cancer potential like aged garlic, visit AntiCancer.news.

Journal Reference:

LV Y, So KF, Wong NK, Xiao J. ANTI-CANCER ACTIVITIES OF S-ALLYLMERCAPTOCYSTEINE FROM AGED GARLIC. Chinese Journal of Natural Medicines. January 2019; 17(1): 43-49.  DOI: 10.1016/S1875-5364(19)30008-1

Originally posted: https://www.naturalnews.com/2019-06-10-compound-from-aged-garlic-demonstrates-anti-cancer-activity.html

Author: 

Chronic exposure to aflatoxins is linked to numerous health problems, such as cancer and kidney damage

aflatoxinsAflatoxins are toxic compounds produced by Aspergillus flavusand Aspergillus parasiticus, two pathogenic fungi that thrive in hot and humid climates. Aflatoxins are some of the most carcinogenic toxins known to man, and they can be found in foods today.

A. flavus and A. parasiticus can contaminate crops in the field, at harvest, and during storage. The aflatoxins they produce are commonly found in corn and corn products, peanuts and peanut products, cottonseed, milk, and tree nuts like Brazil nuts, pecans, pistachio nuts, and walnuts. The most common and deadliest aflatoxin is aflatoxin B1. (Related: How the environment may be promoting cancer (and how you can reduce these effects).)

There have been reports of people consuming normal-looking corn, peanuts, or grain and becoming critically ill or even dying from acute aflatoxin poisoning. Aflatoxicosis, while primarily a liver disease, can also cause brain damage, convulsions, hemorrhage, and pulmonary edema.

An estimated 4.5 billion people are exposed to aflatoxins every year in developing countries. Chronic exposure to aflatoxins can cause the following problems to different systems of the body:

  • Cardiovascular: heart inflammation
  • Circulatory: blood and bone cancers
  • Endocrine: tumors and cancer
  • Gastrointestinal: liver damage, liver cancer, viral hepatitis, or parasite infestation
  • Immune: weakened immunity, autoimmune reactions, and allergies
  • Neurological: reduced oxygen flow, headaches, nerve cell death, encephalopathy, insomnia, disorientation, loss of coordination, impaired memory, and tumor growth in both the central and peripheral nervous systems
  • Reproductive and developmental: infertility, birth defects, abnormal growth and development in children
  • Respiratory: pulmonary edema and lung cancer
  • Urinary: kidney damage and tumor growth

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Aflatoxins cannot be destroyed by cooking or processing food as they are very stable and are capable of surviving relatively high temperatures. Exposure to these toxic substances may also come from eating meat, eggs, milk, and other dairy products, especially if the animals these foods came from were fed aflatoxin-contaminated feed.

Despite this, regulators do not require foods to be aflatoxin-free. In fact, they allow aflatoxins to be present at low levels, disregarding the harm long-term exposure to them might cause. The U.S. Food and Drug Administration (FDA) allows up to 20 parts per billion aflatoxins to be present in foods, while Canada and Australia only allow 15 parts per billion. When it comes to animal feeds, much higher levels of aflatoxins are permitted by the FDA – up to 300 parts per billion.

What you can do to reduce your aflatoxin exposure

You can reduce your aflatoxin exposure by disposing of nuts that look moldy, discolored, or shriveled. If nuts taste sour, bitter, or funky, toss them out as well. If you still want to eat peanut butter, choose organic ones made from Valencia peanuts. They are grown in New Mexico where mold levels are lower because of the dry climate. Eating green vegetables when you consume peanut butter may block aflatoxin absorption because of their chlorophyll content.

Whatever type of peanut butter you choose, always store it in the refrigerator. If you are to make your own, wash your grinder thoroughly. Some studies have also suggested soaking and fermenting nuts and grains to significantly reduce their aflatoxin levels and mitigate the toxic effects of these substances.

For more information on aflatoxins and other cancer-causing substances, visit CancerCauses.news.

Sources include:

GreenMedInfo.com

PoisonousPlants.AnSci.Cornell.edu

Cancer.gov

Originally posted: https://www.naturalnews.com/2019-06-07-chronic-exposure-to-aflatoxins-health-problems-kidney-damage.html
Author: 

TCM niu bang zi Traditional Chinese Medicine herb proven to be a powerful anti-cancer agent

The greater burdock (Arctium lappa) is a popular medicinal plant used in traditional Chinese medicine. Its fruit, known as niu bang zi, is especially well-known: It is used to treat multiple ailments, such as boils, acute tonsillitis, abscesses, and constipation. According to researchers at Wonkwang University in South Korea, the fruit can potentially be used as an anticancer agent. In their study published in The American Journal of Chinese Medicine, they revealed that niu bang zi has antiproliferative and anti-metastatic properties that make it effective against colorectal cancer.

Colorectal cancer, the collective term for cancers that start either in the colon or rectum, is one of the most common cancers in the U.S. Nearly 150,000 cases has been diagnosed in the country for 2019 alone. The American Cancer Society estimates that, overall, the lifetime risk of developing colorectal cancer is about 4.49 percent for males and 4.15 percent for females.

The fruit of the greater burdock can stop the metastasis of colorectal cancer

For their study, the researchers examined the pharmacological properties of niu bang zi and its ability to suppress the growth of colorectal cancer cells. They looked at how the fruit can inhibit cell growth, epithelial-mesenchymal transition (EMT), migration, and invasion of colorectal cancer cells. EMT refers to the process by which epithelial cells assume the characteristics of mesenchymal cells. These characteristics or phenotype include enhanced migratory capacity, invasiveness, and resistance to programmed cell death (apoptosis). While EMT is activated to help with tissue repair in the event of an injury, certain genomic changes within cells can also cause it to generate invasive cells that can spread to other organs.

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Based on the results of in vitro testing using CT26 colorectal carcinoma cells, researchers found that niu bang zi can induce cell cycle arrest and apoptosis, which led to a decrease in CT26 cell proliferation. It also halted metastasis by increasing the expression of E-cadherin, an epithelial marker known for its tumor-suppressing activity. In addition, niu bang zi reduced the expression of the mesenchymal marker, N-cadherin, in CT26 cells. Previous studies have reported that N-cadherin is widely expressed in colorectal cancer cell lines, making it a potential prognostic predictor of colorectal cancer.

The researchers also found that niu bang zi could inhibit matrix metalloproteinase-2 (MMP-2) and MMP-9 activity, which caused a decrease in the invasion and migration capacity of CT26 cells. They associated this decrease with the activation of AMP-activated protein kinase (AMPK). AMPK is considered to be the central regulator of energy homeostasis that balances nutrient supply and energy demand. It is also an important target in therapies designed to control diseases like metabolic syndrome and cancer.

“Collectively, this study demonstrates that [niu bang zi] inhibits the proliferation and metastatic properties of [colorectal cancer] cells,” the researchers concluded. (Related: Fighting colorectal cancer with gut health: Certain probiotic bacteria, combined with broccoli, found to prevent and reduce tumors.)

The findings of this study are similar to those of other studies that investigated the relationship between TCM and colorectal cancer. For instance, a study published in JNCI Monographs revealed that the regular use of TCM herbal medicine can significantly improve the survival outcomes of patients with stage II or III colorectal cancer. The cohort study involved over 300 patients who were monitored over a five-year period.

Learn more ways to prevent colorectal cancer at Cancer.news.

Sources include:

Science.news

Cancer.org

JCI.org

Spandidos-Publications.com

Nature.com

Academic.OUP.com

Originally: https://www.naturalnews.com/2019-06-06-tcm-niu-bang-zi-powerful-anti-cancer-agent.html

Author: 

Cancer survivor praises cannabis oil for ‘saving her life’ after being told she had months to live

A cancer survivor has told how cannabis oil ‘saved her life’.

The comments come after she was told an incurable brain tumor would kill her within just months.

In December 2013 doctors told Lynn Cameron she had just “six to 18 months” to live.

After several session of chemotherapy and radiotherapy, the 48-year-old opted to try cannabis oil in a desperate bid to save her life.

Incredibly, almost four years after her diagnosis, Lynn is still alive and is now pushing “for the reform of the current prohibitive laws around the use of cannabis for medication”.

Lynn explained: “I took a seizure on November 30, 2013, prior to which I had been quite well.

“I had a scan on December 10 and it showed a mass, and I was taken straight into Southern General at that point.

“I was operated on December 16, and on December 27 I was told that I had stage 4 terminal brain cancer.

“So I underwent the chemotherapy and radiotherapy combined, but was told even then I would live six to 18 months at best.

“A good friend suggested cannabis, but I was too scared because it’s illegal. I also found it hard to believe that it would cure brain cancer so advanced.

“But as the scans were showing there was no change to the mass, I eventually thought, ‘I’m going to break the mold here and try that’.”

Lynn, from Blantyre, Scotland, began desperately researching alternative medicines and diets in a desperate attempt to win her battle with cancer, reports the Daily Record.

She continued: “I researched more and more into natural ‘cancer killers’ and decided to follow an alkaline diet and cut out processed foods altogether. I also cut out sugar completely.

“I started taking cannabis oil under my tongue, as it gets straight into the bloodstream that way.

“Each scan I received after that was showing an improvement. I had been told that chemotherapy and radiotherapy don’t make much difference, so I knew it must be the cannabis doing it. By the sixth MRI, cancer had gone.”

Lynn had kept her use of cannabis oil from doctors, but challenged them on the use of the drug after receiving the all-clear.

She added: “The doctors treating me didn’t know about the cannabis oil until I got the results.

“I challenged them on it, but they dismissed it. They weren’t taught about cannabis at medical school – more for a political reason than medical I believe.

“They told me, ‘eat whatever you like, take all the vitamins you want, it won’t work’.

“But these were the people who told me my cancer was incurable, and it was gone.

“The British Medical Journal hasn’t properly investigated cannabis. The irony was they were giving me morphine and codeine in the wards. Prior to becoming ill, I had never taken a pill before in my life.

“It was up to me what treatment I took, and I’m glad I researched it.”

Cannabis oil, which is also known as cannabidiol (CBD), is now available to buy in the UK in pharmaceutical shops.

According to the Cannabis Trades Association UK the number of CBD users has doubled from 125,000, 12 months ago, to 250,000 now.

It has been claimed that it can be beneficial in treating a number of health care issues including pain, symptoms of cancer and stress and anxiety.

But what is cannabis oil made from and what is it used for? Here’s everything you need to know.

What is cannabis oil?

(Image: PA)

Cannabis oil is a thick and sticky substance extracted from the leaves and flowers of the hemp plant. It is also refereed to as CBD (due to the strain it is made from), full extract cannabis oil (FECO) and hash oil.

According to macmillan.org.uk , a cannabis plant produces a resin (sticky flammable organic, insoluble in water) that contains various substances, these are known as ‘cannabinoids’.

The two main types of cannabinoids are:

  • Delta-9-tetrahydrocannabidiol (THC) – illegal in the UK and not used to make cannabis oil
  • Cannabidiol (CBD)

According to cannabis oil manufacturer hertshemp.com, this is the distinction between THC and CBD cannabinoids:

  • Tetrahydrocannabinol (THC)

THC is the most abundant constituent of the cannabis plant, and the most well known. THC is the intoxicating and psychoactive substance that is responsible for causing the marijuana high.

It is considered a controlled substance and is therefore illegal.

  • Cannabidiol (CBD)

The second most abundant compound is Cannabidiol, more commonly known as CBD. This is a non-psychoactive substance, typically representing about 40% of the Cannabinoids in the Cannabis plant. And it’s the effect of this particular Cannabinoid, CBD that is currently being researched in many studies all over the world.

Why is cannabis oil legal?

CBD is not considered a controlled substance and is therefore 100% legal.

It is what cannabis oils being sold in the UK are made from.

What can it be used for?

It can be beneficial for people who suffer from stress, anxiety, depression or lack of sleep. It has also been suggested that it can be used to help alleviate the pain of cancer patients.

However, cancer charity Macmillan.org.uk said: “There are side effects of using cannabis oil. Cannabinoids can increase your heart rate, cause dizziness, hallucinations, paranoia and make you feel ‘stoned’. They may also interact with other drugs.”

It has also been claimed cannabis oil can treat symptoms of Alzheimer’s Disease, Parkinson’s Disease and MS.

Where can I buy it?

(Image: Holland and Barrett)

Holland and Barrett is selling Jacob Hooy CBD+ Oil 2.75% 10ml for £9.49, (it’s currently on offer, the usual RRP is £19.99). Since stocking the product at the high street store, sales of Jacob Hooy have shot up 37 percent.

It began selling the product at the beginning of the year, it is said to be made with cold-pressed hemp seeds. Each 10ml bottle contains approximately 240 drops.

The advice on the bottle’s packaging reads: “CBD+ Oil has a ‘distinctive’ taste – have a small drink of water after taking the oil and the taste will be gone within 30 seconds.”

Users take it orally, by putting a few drops under the tongues 2-3 times a day. Leave the oil in the mouth for one minute before swallowing. The maximum dosage is 15 drops a day.

It has proved to be popular with customers, so much so that Holland and Barrett will be introducing four more CBD products to its range later on in the year.

Holland & Barrett said: “‘We have been surprised at the success and popularity of CBD oil since its launch. We are constantly looking to bring new and innovative ­products to market that help our customers.

“It is great to see in this instance that we can help with the demand.”

Originally posted: https://www.birminghammail.co.uk/news/uk-news/cancer-survivor-praises-cannabis-oil-14341684?fbclid=IwAR255wpaB5XnR–W_0TA7Be76aF0WQwi7dSRz2FadA1_hvGfrumJhJVxsjY

Woman who refused chemo and instead chose ‘injections of a plant’ is now cancer free

Mistletoe cancerIvelisse Page’s family has a history of colon cancer. Her father died from the disease in his late thirties. Knowing that she was at higher risk for developing the illness, she followed a healthy lifestyle of organic food and exercise and got regular colonoscopies, yet she also developed colon cancer at the age of 37.

After the diagnoses, she had 15 inches of the colon with 28 lymph nodes removed, and later 20% of her liver removed, she writes on her website. But there was one important part of the mainstream oncology treatment that she declined to do – after researching her disease and treatment options herself, she completely refused chemotherapy.

Instead, Ivelisse turned to homeopathic remedies and supplements, as well as mistletoe injections – popular alternative cancer treatment in Europe. Seven years later, she is complete cancer free and is happy to say that she beat IV stage colon cancer that only 11% of patients survive.

Mistletoe Injection for Cancer Treatment

Ivelisse’s doctor in Baltimore, Peter Hinderberger, is one of 50 doctors in the U.S. who can prescribe mistletoe treatments. He first heard of this treatment in the 1970s and worked in a Switzerland cancer clinic that specialized in it. Today, mistletoe is the main part of his own cancer protocol. According to Baltimore Sun, mistletoe has a substance called viscotoxin. Although poisonous, mistletoe kills specific cells – targets cancer cells while improving a patient’s immune system simultaneously.

 

A 2007 study found mistletoe extract to extend the life expectancy of patients with ovarian cancer. A European paper from 2001 concluded that mistletoe treatment extended the survival rate of 1,668 patients with all types of cancer by about 40% after studying 27 years worth of research.

Mistletoe: not just for Christmas decorations anymore. PHOTO: By Loadmaster (David R. Tribble), Wikimedia Commons

Will Mistletoe Be Widely Used In The U.S.?

While in some European countries such as Germany, mistletoe therapy is accepted and covered by health insurances (though not the German public one, it is covered by some others), the extract is not approved by the FDA. Ivelisse and Dr. Hinderberger are trying to bring it into mainstream oncology on the U.S.

Suzanne Somers, a well-known actress, singer, and author of Knockouta book about alternative cancer therapies, utilized mistletoe extract injections as part of her natural healing protocol for cancer. But it hasn’t caught on in the U.S. the way it has in Europe just yet.

In 2011, Ivelisse and Jimmy Page founded Believe Big, a nonprofit aimed to educate people on “bridging the gap between conventional and complementary medicine for fighting cancer.” The site also provides resources about mistletoe treatments and how to find physicians who are trained in this therapy.

In 2013, Believe Big started to raise the funds for mistletoe clinical trials at Johns Hopkins Medicine’s Sidney Kimmel Comprehensive Cancer Center. The trials would take 5-8 years to complete and would study patients with different types of cancers. The cost of the trials is high, and the cancer center is still holding fundraisers and a GoFundMe campaign to collect enough money to start the process.

Physicians currently working with mistletoe therapy can be found on BelieveBig.org.

Ivelisse also shares her story in an interview with ChristBeatCancer.com:

Source: AltHealthWorks

How WHOLE Turmeric heals the damaged brain

turmericLong considered impossible to accomplish, compelling research reveals how a simple spice might contribute to the regeneration of the damaged brain.

Turmeric is hands down one of the, if not the, most versatile healing spice in the world with over 800 experimentally confirmed health benefits, and an ancient history filled with deep reverence for its seemingly compassionate power to alleviate human suffering. It may also represent the pharmaceutical industry’s single most existential threat, given that the preliminary science signals turmeric is at least as effective as 14 drugs, and much safer as far as toxicological risk.

RELATED STORY:

But, most of the focus over the past decade has been centered on only one of its many hundreds of phytocompounds: namely, the primary polyphenol in turmeric known as curcumin which gives the spice its richly golden hue. This curcumin-centric focus has lead to the development of some very good products, such as phospholipid bound curcumin concentrate (e.g. Meriva, BCM-95) which greatly helps to increase the absorption and bio-activity of curcumin. But, curcumin isolates are only capable of conferring a part of turmeric’s therapeutic power – and therein lies the limitation and hubris of the dominant ‘isolate the active ingredient’ model.

RELATED STORY:

Indeed, it has become typical within the so-called nutraceutical industry to emulate the pharmaceutical model, which focuses on identifying a particular “monochemical” tree within the forest of complexity represented by each botanical agent, striving to standardize the delivery of each purported ‘active ingredient’ with each serving, as if it were a pharmaceutical drug. These extraction and isolation processes also generates proprietary formulas which are what manufacturers want to differentiate their product from all others and henceforth capture a larger part of the market share; a value proposition that serves the manufacturer and not the consumer/patient.

Truth be told, there is no singular ‘magic bullet’ in foods and herbs responsible for reproducing the whole plant’s healing power. There are, in fact, in most healing plants or foods hundreds of compounds orchestrated by the intelligent ‘invisible hand’ of God or ‘Nature,’ or whatever you wish to call it, and which can never be reduced to the activity of a singularly quantifiable phytocompound or chemical.

Beyond The Curcumin ‘Magic Bullet’ Meme

Recently, a study published in the journal Stem Cell Research & Therapy provides additional support for the concept that curcumin alone is not enough to explain the healing power of turmeric as a whole plant. The study found that a little known, fat-soluble component within turmeric – Ar-tumerone – may make “a promising candidate to support regeneration in neurologic disease.”

Titled, “Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo,” German researchers evaluated the effects of this turmeric-derived compound on neural stem cells (NSCs) – the subgroup of brain cells capable of continuous self-renewal required for brain repair.

The study found that when brain cells were exposed to ar-tumerone, neural stem cells increased in number through enhanced proliferation. Moreover, these newly formed neural stem cells also increased the number of fully differentiated neuronal cells, indicating a healing effect was taking place. This effect was also observed in a live animal model, showing that rats injected with ar-tumerone into their brains experienced increases in neural stem cell proliferation and the creation of newly formed healthy brain cells.

RELATED STORY:

This study did not go unnoticed by major medical news channels. Here are some good reviews if you wish to explore the implications in greater depth:

  • Newsweek: Curry Power: Turmeric Compound Boosts Growth of Brain’s Stem Cells
  • Guardian Liberty Voice: Turmeric Cure Evidence Grows
  • Monthly Prescribing Reference: Turmeric May Help Regenerate Brain Cells
  • Times of Malta: Turmeric Link to Brain Cell Repair
  • Medical Daily: Turmeric Helps Your Brain Heal Itself: Spice Up Your Brain

The GreenMedInfo.com Turmeric Database Confirms It’s Brain-Saving Power!

As you may already know, our database is the world’s most extensive open access natural medical database on over 1,600 different natural substances, with over 2000 study abstracts on turmeric’s healing properties indexed thus far: view the Turmeric research page here to view! (Watch the video below for more details about our public resource).

If you take a look at the laundry list of over 800 diseases that this spice (or its components, e.g. curcumin) has been studied for to prevent and/or treat, the sheer volume of supportive literature is astounding. Amazingly, we have identified over 270 physiological pathways – according to their conventional pharmacological characterization, e.g. COX-2 inhibitor, Interleukin 6 down-regulator – by which turmeric or its components heals the human body. In addition, you will find over 217 articles on turmeric’s neuroprotective properties on this page: Turmeric as a Neuroprotective agent. (Find out how we generate these results in the video below)

The research clearly indicates that turmeric is a great brain supportive plant. For a more layperson oriented review, read the following articles:

  • How Turmeric Can Save the Aging Brain From Dementia
  • Turmeric Produces ‘Remarkable’ Recovery in Alzheimer’s Patients
  • The Spice That Prevents Fluoride From Destroying Your Brain

How To Get The Most Out of Your Turmeric

One of the most frequent questions we field is ‘what is the best type of turmeric or curcumin to use’? Obviously, given the aforementioned research, the whole plant is going to carry a wider range of therapeutic compounds than curcumin alone. And yet, most have been heavily enculturated to focus entirely on the ‘how much’ question, opting to identify the molecular weight (i.e. how many milligrams in a serving) of a particular compound as more important than the qualitative dimensions (e.g. is it organic? It is delivered within its natural context as food or a whole plant?) which reflect the type of nutrigenomic information the substance contains, and therefore the ‘intelligence’ it embodies. To learn more about the intelligence of food watch my e-course with Ayurvedic master herbalist KP Khalsa, which is available (along with a database of educational videos) for free as a member.

And really, there is no generic answer to a generic question about the best way to take turmeric/curcumin. The question always comes from an individual with a particular need, and so, recommendations must be bio-individualized.

For instance, if you have colonic inflammation or polyps, and you are trying to use turmeric to reduce inflammation there or regress precancerous growths, then using the whole plant is best versus a highly bioavailable form of curcumin in capsule form (e.g. Meriva), for instance, which will likely be absorbed by the small intestine and mostly pass through the liver never getting adequate quantities to the large intestine. So, in this person’s case taking a teaspoon of relatively difficult to absorb turmeric may result in painting the diseased surfaces of that person’s intestinal or colonic lumen with exactly the form needed to reverse disease.

But what if you have someone who wants to experience a systemic effect, say, for arthritis or for brain cancer? In these instances, getting turmeric compounds such as curcumin through the glucuronidation barrier in the liver with a phospholipid-bound or black pepper (piperine) combination could be ideal. There is certainly a place for the ‘nutraceutical’ model when properly applied, especially when provided as an adjuvant to the pharmaceutical model within an integrative medical setting.

Ultimately, the goal is not to wait to have such a serious health problem that you have to force yourself to take a ‘heroic dose’ of any herb or food extract. Better is to use small amounts in culinary doses in combination with ingredients that synergize on a physiochemical/informational and sensual basis (producing the all important vitamin P [pleasure] as well!). Recently we actually featured a study that showed culinary doses of rosemary helped improve memory whereas higher ‘heroic’ doses impaired it!

This is why exploring the use of turmeric in curries, or by adding a pinch in a smoothie, may be an ideal daily supplementation approach, versus capsules, whose questionably ‘natural’ capsules and excipients all can add up to cause some stress on the liver you are trying to protect with these natural interventions. Just remember quality is everything and less is more!

Sayer Ji

*Article originally appeared at Green Med Info.

Chronic renal failure can be alleviated using Chinese chives

renal failureChronic kidney failure, also known as chronic kidney disease, is a progressive and potentially life-threatening condition in which the kidneys are damaged and can’t filter blood properly. A study published in the journal Food Science and Human Wellness found a natural solution to this debilitating disease that can also improve kidney function: Chinese chives.

Chinese chives (Allium tuberosum), also known as garlic chives, are a well-known green vegetable in China used in traditional Chinese medicine to treat impotence and nocturnal emissions. Other allium plants have been shown to have kidney-protective effects. Therefore, researchers from Hefei University of Technology in China looked at the protective effects of Chinese chive extracts against chronic kidney failure in mice. (Related: Try this instead of oysters: Garlic chives are a natural way to increase libido and treat erectile dysfunction.)

In the study, the researchers administered adenine to mice to induce chronic kidney failure. They then treated the animals for five weeks with water or ethanol extracts obtained from Chinese chives. The administration of adenine caused damage to the kidneys of mice and increased the levels of creatinine and urea nitrogen in their blood. High levels of serum creatinine and blood urea nitrogen indicate impaired kidney function.

However, these damages caused by adenine were reduced upon treatment with Chinese chive water extracts. The Chinese chive water extract significantly reduced renal pathological damages, serum creatinine, and blood urea nitrogen levels. At the same time, it significantly inhibited oxidative stress and inflammation in the kidneys of mice with chronic kidney failure. These results indicated that Chinese chive water extracts can improve kidney function in mice with chronic kidney failure by increasing the antioxidative activity and inhibiting inflammation in the kidneys. With these findings, the researchers concluded that Chinese chive water extracts may be used to develop a functional food supplement that can treat chronic kidney failure.

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Chronic kidney failure affects about 30 million Americans. People with diabetes, hypertension, or heart disease, those who have a family member with kidney disease, and people aged over 60 have a higher risk of developing the condition. Many people who suffer from chronic kidney failure may also experience complications like anemia, bone disease, heart disease, high potassium, high calcium, and fluid buildup.

Other benefits of Chinese chives and how to add them to your diet

In addition to their kidney-protective effects, Chinese chives provide other health benefits. Chinese chives are rich in vitamin C, which helps protect against the common cold and fever. Chinese chives also have high amounts of beta-carotene, iron, potassium, riboflavin or vitamin B2, thiamin or vitamin B1, and vitamin A – all of which help increase blood count, regulate blood pressure, and boost immunity. Moreover, Chinese chives are low in fat, which means that they are safe for people suffering from obesity to consume.

Chinese chives are also rich in fiber, which can help prevent digestive problems like constipation, and lower the risk of developing colon cancer. The antioxidant effects of vitamin A and vitamin C, together with its high fiber content, enable Chinese chives to help prevent cardiovascular problems. In addition, these chives are also rich in protein, which works together with fiber to maintain a healthy and balanced metabolism.

These herbs are commonly used for cooking in China and other Asian countries. Chinese chives have a mild garlic flavor, which is a good choice for those who don’t like the fuller flavor of garlic. Chinese chives are used the same way as regular chives; they can be added in salad dressings and soups, or used as a garnish. They are also used in spring rolls, chow mein, and scrambled eggs.

Read more about Chinese chives and other natural foods that can help with kidney problems at FoodScience.news.

Sources include:

Science.news

ScienceDirect.com

KidneyFund.org

OnlyFoods.net

Spiceography.com

TheSpruceEats.com

Originally posted: https://www.naturalnews.com/2019-05-27-chronic-renal-failure-can-be-alleviated-with-chinese-chives.html
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Gotta love the love apple: It prevents osteosarcoma from spreading

osteosarcomaParis polyphylla, also known as love apple, is a perennial herb that can be found mostly in South East Asia. This medicinal plant is a member of the Melanthiaceae family and it has found wide usage in traditional Chinese medicine. According to studies, P. polyphylla possesses antimicrobial, anti-tumor, and anticancer properties. To determine its potential as an anticancer agent, particularly against osteosarcoma, the most common cancer in the bones, researchers from Nanjing University in China tested P. polyphylla extracts against different osteosarcoma cell lines. They also investigated the mechanisms underlying its activity. The results of their study were published in The American Journal of Chinese Medicine.

P. polyphylla extracts against bone cancer

In traditional Chinese medicine, P. polyphylla is known as an antipyretic (reduces fever) and a detoxifying agent. But for thousands of years, it has also been applied extensively in cancer treatments. To evaluate its anti-osteosarcoma effects, the Chinese researchers obtained P. polyphylla extracts using ethanol as solvent. They then tested the antiproliferation activity of the P. polyphylla ethanol extracts (PPEE) on 143B, MG-63, U-2 OS, and hFOB1.19 cells using MTT assay. (Related: Stage-4 bone marrow cancer reversed naturally.)

143B cells are commercially available human osteosarcoma cells that are thymidine kinase negative. Thymidine kinase is an enzyme that plays a role in the salvage pathway of DNA synthesis and whose levels are indicative of proliferation. MG-63 and U-2 OS are also human osteosarcoma cell lines; MG-63 cells have fibroblast-like morphology while the U2-Os cell line, one of the first cell lines to be generated, exhibits epithelial-cell-like morphology. hFOB1.19 cells, on the other hand, are human osteoblasts or bone cells.

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To confirm the pro-apoptotic and cell-cycle effects of PPEE, the researchers used Hoechst 33342 staining and flow cytometry. Hoechst 33342 staining uses a fluorescent dye to stain the DNA and nuclei of cells. It is especially useful in determining cell death or apoptosis. They also used Transwell and 3d culture assays together with wound healing to investigate the anti-migratory, anti-invasive, and anti-vasculogenic mimicry effects of PPEE. Transwell assay is a migration assay used to study the migratory response of epithelial cells.

Lastly, they used a mouse xenograft (tissue graft) model to determine the anti-osteosarcoma efficacy of PPEE in vivo and assessed its toxicity using hematologic profiles and evaluation of hepatorenal functions.

P. polyphylla suppresses proliferation, tumor-formation of bone cancer cells

The researchers reported that PPEE was able to suppress the proliferation of 143B, MG-63, and U2-OS cells. Interestingly, it showed little cytotoxicity against normal osteoblastic cells, suggesting a favorably selective anti-proliferation activity that leaves normal cells unaffected.

PPEE also promoted apoptosis in 143B cells via caspase activation, increased Bax/Bcl-2 ratio, and PARP cleavage. Caspases are enzymes involved in programmed cell death and activation of caspases, in particular, caspase-3, which inactivates the PARP protein. PARP cleavage is a marker of caspase-mediated cell death while upregulation of Bax/Bcl-2 ratio is also associated with apoptosis.

In terms of cell cycle effect, PPEE induced G2/M phase arrest associated with elevated phosphorylation of CDK1, Cdc25C, Chk2, and the down-regulation of cyclin B1, CDK1, Cdc25C expression. The G2 phase is where cell repair and preparation for mitosis (M phase) occurs. According to studies, arresting the G2/M phase enhances cell apoptosis.

PPEE also inhibited 143B cell migration, invasion, and vasculogenic mimicry (VM) at noncytotoxic concentrations by decreasing the expression of FAK, Mig-7, MMP2, and MMP9. VM is a blood supply system independent of endothelial cells that is found in tumors. The presence of VM is associated with a high tumor grade, short survival, invasion, and metastasis.

In vivo, daily oral administration of PPEE for four weeks also showed potent antitumor and anti-VM activity in 143B xenograft models with low toxicity.

Based on these results, the researchers concluded that PPEE possesses anti-VM and anti-osteosarcoma activity in vitro and in vivo, making it a potential candidate for osteosarcoma treatment.

Sources include:

Science.news

ScienceDirect.com

ATCC.org 1

ATCC.org 2

ThermoFisher.com

ClinCancerRes.AACRJournals.org

Molecular-Cancer.BiomedCentral.com

Originally posted: https://www.naturalnews.com/2019-05-22-love-apple-prevents-osteosarcoma.html
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Colloidal silver made with Ghanera extract has anticancer and antimicrobial potential – study

Ghanera extractGhanera (Nothapodytes nimmoniana) is a small flowering tree found in India. It bears oblong fruits which are purplish when ripe and contain only single seeds. Ghanera is known as a rich source of camptothecin (CPT), a topoisomerase inhibitor that can potentially treat ovarian and small lung cancers. Recently, researchers from Bharathidasan University in India discovered another application for ghanera: Its fruit extract can be used as a capping agent in the biosynthesis of nanoparticles that have strong anticancer and antimicrobial activities.

Why nanoparticles?

Nanoparticles have long been studied due to their potential in drug delivery. Researchers prefer to use them because they can be engineered to suit a specific purpose; for instance, they can target only diseased cells to allow for direct therapy. Nanoparticles, when used as vehicles, also reduce the damage done to healthy cells in the body because they can be more specific. They are also useful in medical diagnosis as they allow for the early detection of diseases.

Metal nanoparticles, on the other hand, are good stabilizing agents in the synthesis of nanoparticles because of their electrical, optical, chemical, and mechanical properties. In this study, published in the journal Food Science and Human Wellness, the researchers synthesized silver nanoparticles (AgNPs) and used a liquid extract from ripe ghanera fruit as capping agent. Capping agents are often used in the synthesis of colloids to stop overgrowth and control the structural characteristics of nanoparticles.

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The researchers characterized the AgNPs they produced using UV analysis and x-ray diffraction. They used scanning electron microscopy to confirm that the AgNPs had a spherical shape and that the particles differed in size.

AgNPs made with ghanera fruit extracts can defend against bacteria and kill cancer cells

The researchers compared the ghanera fruit extract and the AgNPs in terms of phenolics, tannins, and flavonoid content. As they expected, the fruit extract had higher amounts of each compound than the AgNPs. It also exhibited better antioxidant activity, proving that the ghanera fruit is rich in phytochemicals that can fight oxidative stress.

In terms of antimicrobial activity, AgNPs proved to be more potent against Bacillus subtilisPseudomonas aeruginosaKlebsiella pneumoniaeStaphylococcus aureus, and Escherichia coliB. subtilis causes gastrointestinal tract infection in humans while P. aeruginosaK. pneumoniae, and S. aureus cause respiratory tract infections. E. coli is part of the normal human gut microflora, but some strains can cause urinary tract infections, abdominal cramps, anemia, and even kidney failure.

The researchers found the AgNPs with smaller particle sizes to be more effective against bacteria due to their large surface areas. Having large surface areas, they explained, meant that there was more space for interacting with bacteria. They also proposed that AgNPs kill bacteria by attaching to their cell surface and disrupting their permeability and respiration. AgNPs may also have the ability to penetrate inside bacterial cells.

When researchers tested the cytotoxicity of both ghanera extract and AgNPs on HeLa cells, they found that AgNPs can inhibit the proliferation of that cancer cell line. They observed that cell viability decreased as they increased the concentration of AgNPs, suggesting that AgNPs have strong anticancer potential. (Related: Rhubarb can destroy cancer cells.)

Based on their findings, the researchers concluded that AgNPs synthesized using ghanera fruit extract can be a promising candidate for biomedical applications due to their potent antimicrobial and anticancer activities.

Sources include:

Science.news

ScienceDirect.com

NCBI.NLM.NIH.gov

UnderstandingNano.com

Pubs.ACS.org

Originally posted: https://www.naturalnews.com/2019-05-22-colloidal-silver-with-ghanera-extract-anticancer-antimicrobial.html